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Epigenetics, Second EditionFrom Cold Spring Harbor Laboratory Press
Download PDF Epigenetics, Second EditionFrom Cold Spring Harbor Laboratory Press
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In many biological processes the regulation of gene expression involves epigenetic mechanisms. In this new edition of Epigenetics, 36 chapters written by experts in the field introduce and explain epigenetic effects from many perspectives. These include the varied molecular mechanisms underpinning epigenetic regulation, discussion of cellular processes that rely on this kind of regulation, and surveys of model organisms in which epigenetic effects have been most studied.
The original chapters have all been rewritten and brand new chapters cover topics such as the structure, function, and dynamics of histone-modifying enzymes and histone-interacting proteins. Other chapters address chromatin remodeling, DNA methylation, siRNAs, and gene silencing; X-chromosome inactivation, dosage compensation, and imprinting; and epigenetics in microbes, plants, insects, and mammals.
How epigenetic mechanisms act in cell division and cell type specification, and how errors in these pathways contribute to cancer and other human diseases are also considered, along with the importance of epigenetics for induced pluripotency and reprogramming. In addition, new chapters describe the involvement of epigenetic processes in epigenetic inheritance, neuronal development, metabolism and signaling, responses to the environment, and long-range chromatin interactions. A series of short essays highlight important recent discoveries.
All the chapters provide conceptual illustrations that help readers understand epigenetic control. The book is thus a benchmark text for advanced undergraduate and graduate courses on gene regulation, as well as an essential resource for scientists interested in this rapidly moving field.
- Sales Rank: #354524 in Books
- Published on: 2015-02-28
- Original language: English
- Number of items: 1
- Dimensions: 8.90" h x 1.80" w x 11.10" l, .0 pounds
- Binding: Hardcover
- 984 pages
Review
"...the second edition of Epigenetics by Cold Spring Harbor Laboratory Press stands out as one of the most comprehensive references for all major developments and perspectives in the field... All chapters are written by prestigious researchers and are nicely organized...the book targets a broad audience and can easily serve as an educational resource in specialized higher level undergraduate and graduate university courses or as a reference for advanced level scientists. Its breadth of topics makes it a compulsory item on the shelf of every lab that is closely or remotely involved in epigenetic studies." ---Frontiers in Genetics
Most helpful customer reviews
2 of 2 people found the following review helpful.
An instant Classic, Superb
By x
Once in a while a scientific book comes along that sets the bar high for anyone to follow, an instant classic. "Epigenetics" is superbly organized into 36 chapters, most with a summary, overview and conclusions. This well organized 984 page second edition is what scientific books should be...easy to read for anyone. Each chapter is broken down into sections with the title of each section expressing an idea or concept. I have not read any books by CSH press before, but I surely will look for them in the future. Needless to say that this book is by far the most advanced resource on this subject today.
0 of 1 people found the following review helpful.
It's excellent for undergraduated students intrested in this subject
By GioS
Epigenetics second edition it's a very well structured book. It's excellent for undergraduated students intrested in this subject.
0 of 2 people found the following review helpful.
Five Stars
By UCLA - Hematology-Oncology
Wonderful book.
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